• List the five major GI hormones and give one function associated with each
• List the two paracrines relevant for the gut and give the major function associated with each
• Describe the role of VIP/NO, enkephalins and GRP in the gut
• Describe the functions of saliva
• List the major products of saliva
• Explain the two stage model for the formation of saliva
• Describe mechanisms underlying formation of primary and secondary saliva
• Explain why saliva is hypotonic and alkaline
• Contrast the pathways for stimulus/secretion coupling in the salivary gland
• State the main pathways regulating salivary secretion
• Describe the cellular mechanisms underlying acid secretion
• Explain the two component model of gastric section and state how the ionic composition of gastric juice changes with flow rate
• List the transporters and channels involved in the generation of gastric juice
• Discuss the role of negative feedback in the regulation of acid secretion
• Describe the role of nerves, hormones, foodstuffs and distension in the regulation of gastric secretion
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