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Respiratory Lecture 9 - Sleep and Control

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Syllabus Ch 7 and 16 7: At the end of the chapter you should be able to: 􀀁 Describe the feedback control loop of breathing 􀀁 Review the major "inputs" to respiratory-related regions in the brainstem including the function of various airway and lung receptors 􀀁 Describe the ventilatory response to PaCO2 and its origin 􀀁 Describe the ventilatory response to hypoxia and its origin 􀀁 Describe the role of the blood-brain barrier in acute and chronic responses to hypoxia, PaCO2, and acid-base disturbances 16: At the end of this chapter you should be able to: 􀀁 Describe the physiologic changes that predispose to SDB 􀀁 Describe the pathophysiology of obstructive sleep apnea (OSA), central sleep apnea (CSA), and sleep-related hypoventilation (SRHV) 􀀁 Discuss the clinical features and sleep study findings in the 3 types of SDB 􀀁 Delineate a treatment approach to the three forms of SDB

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